Osteomeasure
Description
Overview
OsteoMetrics has been part of the bone histomorphometry community since 1989, serving researchers from major research institutions, CROs and pharmaceutical companies. Our main product OsteoMeasure has been used in over 400 laboratories all over the world. It was designed specifically for bone histomorphometry, following standard ASBMR nomenclature.
Professional and efficient bone tissue morphology measurement and analysis, quantitative analysis of commonly used static and dynamic parameters of bone remodeling. Automatically calculate over 340 bone parameters, explaining the causes and processes of bone tissue morphological changes from the cell biological perspective. Static parameters include: Bone Volume/Tissue Volume (BV/TV), Trabecular Thickness (Tb.Th), Trabecular Number (Tb.N), Trabecular Separation (Tb.Sp), Osteoblast Surface/Bone Surface (Ob.S/BS), Osteoid Surface/Bone Surface (OS/BS), Osteonal Osteoid Surface (On.OS/BS), Number Osteoblasts/Bone Perimeter (N.Ob/B.Pm), Number Osteoclasts/Bone Perimeter (N.Oc/B.Pm), Osteoclast Surface/Bone Surface (Oc.S/BS), osteoclast surface area The dynamic parameters include: Mineralization Apposition Rate (MAR), Mineralizing Surface/Bone Surface (MS/BS), Eroded Surface/Bone Surface (ES/BS), Bone Formation Rate/Bone Surface (BFR/BS), Mineralized Area (Md.Ar), Activation Frequency (Ac.f), Osteoclast Surface/Bone Surface (Oc.S/BS), Osteonal Mineralizing Perimeter (On.M.Pm), Periosteal Mineralizing Perimeter (Ps.M.Pm), etc.
Features
Effective and Efficient Measuring Tools
Graphical overlays on live digital imaging for fast and efficient semi-automatic measurement
Publication quality images at all magnifications with 20 Mpixel digital camera
Ergonomic QHD Pen Touch Monitor for fast, efficient manual tracing
Support for measurement of TIFF images
Support for scanned image datasets
Journal Citations
l Mathias Sch?fersküpper, et al., “Reconstructing skeletal homeostasis through allogeneic hematopoietic stem cell transplantation in myelofibrosis”, nature communications, volume 16, Article number: 741 (2025)
l Ok-Jin Park, et al., “The dual roles of peptidoglycans: NOD1 and NOD2 inversely regulate bone metabolism“, Experimental & Molecular Medicine volume 57, pages1837–1846 (2025)
l Yu You, et al., “GnIH secreted by green light exposure, regulates bone mass through the activation of Gpr147”, Bone Research volume 13, Article number: 13 (2025)
l Yuying Li, et al,. “MTHFD2 promotes osteoclastogenesis and bone loss in rheumatoid arthritis by enhancing CKMT1-mediated oxidative phosphorylation”, BMC Medicine, Volume 23, article number 124, (2025)
l Lu Zhang, et al., “GLUL mediates FOXO3 O-GlcNAcylation to regulate the osteogenic differentiation of BMSCs and senile osteoporosis”, Cell Death & Differentiation (2025)
Xiaoting Zhang, et al., “Augmenting osteoporotic bone regeneration through a hydrogel-based rejuvenating microenvironment”, Bioactive Materials, Volume 41, November 2024
